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An effective postibiotic diarrhea treatment

Lactéol® is an effective postbiotic treatment for diarrhea, engineered using our innovative microbiome technology platform. It is composed of our proprietary postbiotic combination of Lactobacillus LB and fermented culture medium. Given in addition to rehydration and dietary measures, Lactéol® helps fight diarrhea in children and adults by inhibiting pathogens and boosting immunity. Today, it is marketed as an Rx and OTC drug in 38 countries around the world.

Why use Lactéol®?

RELIABILITY:
A scientifically proven ingredient

Lactéol®’s safety and efficiency are supported by over 100 years of scientific research. The active postbiotic ingredient, Lactobacillus LB and fermented culture medium, have been the subject of extensive scientific studies. In the last 30 years alone, almost 40 peer-reviewed publications on Lactobacillus LB have been published, making Lactéol® one of the most documented biotic-based treatments on the market.

EFFICIENCY: Helps treat diarrhea

Studies have proven that Lactéol® shortens the duration of diarrhea and improves stool consistency1,2. Not only is Lactéol® effective, but it is also fast acting: its benefits are observed in less than 24 hours.

Moreover, the efficacy of Lactéol® has been demonstrated in different types of diarrheas. In adult populations, Lactéol® has been proven effective on acute diarrhea1, antibiotic-associated diarrhea2, chronic diarrhea and irritable bowel syndrome (IBS)3. In children, studies show an effect on non-rotavirus diarrhea4, rotavirus-positive diarrhea5, and in mild and acute diarrhea6.

SAFETY:
Good safety profile

Because it is heat-treated, Lactéol® has an excellent safety profile. It is well tolerated by all age groups with no serious side effects. Lactéol® can be safely administered to both young children and the elderly to treat diarrhea. Moreover, Lactéol® is included in the ESPGHAN (European Society of Pediatric Gastroenterology Hepatology and Nutrition) 2014 recommendations for diarrhea management and treatment7.

How does Lactéol® work?

Lactéol® its efficacy in diarrhea management in two ways. Firstly, it shortens the duration of diarrhea. Secondly, it reduces stool frequency. These effects can be explained by 3 mechanisms of action:

  • Fights pathogens;
  • Stimulates the body’s natural defenses which help prevent potential infections;
  • Stimulates the natural beneficial bacteria of the gut to reinforce the balance of what?
Lacteol

How to use Lactéol®?

Easy storage

Due to the inactivation step of the ECHO™ process used to produce its active ingredient, Lactobacillus LB, Lactéol® is particularly stable. It can be stored at room temperature and is easy to transport and store. This is particularly crucial in countries where diarrhea in children is endemic and where it is difficult to maintain the cold chain.

Convenient administration

Lactéol® exists in a variety of formats, suitable for all members of the family:

  • Powder sachets for oral suspension, suitable for all ages
  • Capsules for ages 6 and older

Each capsule or sachet contains either 5 or 10 billion heat-treated Lactobacillus LB and the culture medium actives.

Finally, because it is highly stable, Lactéol® can be administered with other drugs such as antibiotics or antifungals. There is no risk of interaction with other systemic medications.

1. Salgado AJ, Garcia Jara JA. Treatment with Lactéol® Fort of adults suffering from acute diarrhea in Mexico. Rev Hosp Mujer 1993;2:61-3.

2. Yap Soo Kor JA, Gwee Kok A, Chen ZA, Tai Bee Choo A, Wong Mee L. Lacteol® Fort treatment reduces antibiotic associated diarrhea. Singapore Fam Physician 2010;34:46-9.

3. Tarrerias AL, Costil V, Vicari F, et al. The effect of inactivated Lactobacillus LB fermented culture medium on symptom severity: observational investigation in 297 patients with diarrhea-predominant irritable bowel syndrome. Dig Dis 2011;29:588-91.

4. Liévin-Le Moal V, Sarrazin-Davila LE, Servin AL. An experimental study and a randomized, double-blind, placebo-controlled clinical trial to evaluate the antisecretory activity of Lactobacillus acidophilus strain LB against nonrotavirus diarrhea. Pediatrics 2007;120:e795-803.

5. Simakachorn N, Pichaipat V, Rithipornpaisarn P, Kongkaew C, Tongpradit P, Varavithya W. Clinical evaluation of the addition of lyophilized, heat-killed Lactobacillus acidophilus LB to oral rehydration therapy in the treatment of acute diarrhea in children. J Pediatr Gastroenterol Nutr 2000;30:68-72.

6. Salazar-Lindo E, Figueroa-Quintanilla D, Caciano MI, Reto-Valiente V, Chauviere G, Colin P. Effectiveness and safety of Lactobacillus LB in the treatment of mild acute diarrhea in children. J Pediatr Gastroenterol Nutr 2007;44:571-6.

7. Szajewska H, Guarino A Fau – Hojsak I, Hojsak I Fau – Indrio F, et al. Use of probiotics for management of acute gastroenteritis: a position paper by the ESPGHAN Working Group for Probiotics and Prebiotics.